MAGENTIQ-COLO™

by Magentiq Eye  · Based in Israel → — Setting the new standard of AI-aided colonoscopy for enhanced polyp detection and improved patient outcomes.
Colorectal Surgery Gastroenterology

Regulatory Status Disclosed

Overview

MAGENTIQ-COLO™ by Magentiq Eye is an AI-powered computer-aided detection (CADe) and computer-aided diagnosis (CADx) system designed to assist gastroenterologists during colonoscopy procedures. It utilizes deep learning, computer vision, and video analysis technologies to provide real-time detection and highlighting of suspicious lesions and polyps, enhancing the physician’s attentiveness and improving diagnostic accuracy. The system also offers advanced features such as polyp size estimation, characterization, and AI-based endoscopic tool detection. It integrates seamlessly into the clinical workflow, acquiring digital video signals from existing endoscopy towers and presenting detected polyps with bounding boxes on a separate screen or the main monitor. MAGENTIQ-COLO™ has demonstrated significant improvements in adenoma detection rate (ADR) and a reduction in adenoma miss rate (AMR) in clinical studies, contributing to earlier detection of colorectal cancer and potentially saving lives. Beyond real-time assistance, the system supports procedural quality (CAQ) metrics, including automated Boston Bowel Preparation Score assessment and cecum detection, and enables structured reporting with exportable videos and procedure summaries.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Real-time polyp detection (CADe)
  • Polyp size estimation and characterization (CADx)
  • AI-based endoscopic tool detection
  • AI-based procedural quality (CAQ) metrics (e.g., Boston Bowel Preparation Score Assessment, Automated Cecum Detection)
  • Highlights suspicious areas with bounding boxes
  • Records and exports videos with or without highlighting
  • Generates procedure reports including duration and findings
  • Seamless integration with existing endoscopy towers (compatible with Sonoscape, Olympus, Fujinon, Pentax)
  • Automatic software updates
  • Validated by large, multi-center clinical studies

Use Cases

  • Improving adenoma detection rate (ADR) during colonoscopy
  • Reducing adenoma miss rate (AMR)
  • Assisting physicians in real-time decision-making during endoscopic procedures
  • Enhancing the overall quality of colonoscopy examinations
  • Contributing to earlier detection and prevention of colorectal cancer
  • Enabling structured reporting for colonoscopy procedures

What Physicians Need to Know

Polyp Detection During Colonoscopy
MAGENTIQ-COLOu2122 is a computer-aided detection (CADe) system that assists gastroenterologists in real-time polyp detection during colonoscopy, highlighting suspicious areas with bounding boxes. It boasts 100% polyp-wise sensitivity and 72% frame-wise sensitivity with 97% specificity. The system also provides real-time information on polyp size category and type.
Real-Time Endoscopy AI
The system operates in real-time by acquiring digital video output signals from the local endoscopy tower and applying deep learning algorithms to highlight detected polyps on the main or a separate screen during the procedure.
Adenoma Detection Rate Improvement
Clinical studies have demonstrated that MAGENTIQ-COLOu2122 increases the Adenoma Detection Rate (ADR) by 26% in relative values (7% absolute increase) and reduces the Adenoma Miss Rate (AMR) by 48% in relative values (17% absolute decrease). It also enhances the detection of small adenomas (6mm-9mm).
GI Pathology Analysis
The CE-marked version of MAGENTIQ-COLOu2122 includes computer-aided diagnosis (CADx) capabilities for real-time polyp size estimation and characterization, which can aid in clinical decision-making regarding polyp management.
Procedure Documentation
MAGENTIQ-COLOu2122 generates a comprehensive report at the conclusion of the procedure, detailing duration and findings, which can be exported. The CE-marked version further enhances documentation with AI-based procedural quality (CAQ) metrics, automated Boston Bowel Preparation Score (BBPS) assessment, and automated cecum detection. Future versions are planned to include advanced reporting features like withdrawal time, cleansing level, and direct EHR integration.
Quality Metrics Tracking
The system contributes to improved quality metrics by significantly increasing ADR and decreasing AMR. The CE-marked version offers AI-based procedural quality (CAQ) metrics, automated BBPS assessment, and automated cecum detection, providing objective data for quality assurance.
Endoscopy System Compatibility
MAGENTIQ-COLOu2122 is designed for compatibility with leading endoscopy systems, including Olympus, Fujinon, Pentax, and Sonoscape, by acquiring digital video output signals from existing endoscopy towers.
Physician Tip

Leverage MAGENTIQ-COLOu2122 as a tireless 'second eye' to enhance polyp detection and reduce miss rates during colonoscopies, particularly for subtle or transient lesions. Utilize the real-time polyp size and type characterization to inform immediate clinical decisions. Integrate the automated reporting and quality metrics for streamlined documentation and to consistently meet and exceed quality standards. Future versions are expected to include AI tools for IBD Mayo scoring and early dysplasia detection in IBD and Barrett's esophagus, expanding its utility in specialized GI diagnostics.

MAGENTIQ-COLOu2122 is engineered for seamless integration into existing colonoscopy workflows, connecting directly to standard endoscopy towers. It is compatible with major endoscopy manufacturers like Olympus, Fujinon, Pentax, and Sonoscape, ensuring broad applicability without requiring significant changes to current equipment setups. The system also features AI-based endoscopic tool detection to temporarily remove overlays when instruments enter the field of view, maintaining an unobstructed view during interventions.

Details

Category Gastroenterology AI
Pricing Unknown — Monthly rental business model; low upfront cost; flexible commitment.
DeploymentOn-premise (integrates with local endoscopy tower hardware; available as processor-only unit or portable cart with touchscreen).
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

MAGENTIQ-COLO™ received U.S. FDA 510(k) clearance on July 25, 2023 (K223473) as an AI gastrointestinal software system intended to be used by endoscopists as an adjunct to common video colonoscopy procedures for real-time lesion detection.

Integrations
EHR Not specified
Specialties Colorectal Surgery, Gastroenterology

What the Web Says

MAGENTIQ-COLOu2122 is an AI-powered colonoscopy assistance system designed to improve adenoma detection rates (ADR) and reduce missed polyps. It provides real-time detection and characterization of polyps during colonoscopies, aiming to enhance the diagnostic accuracy of endoscopists. The system integrates with existing endoscopy equipment and offers features like visual alerts and AI-driven insights.

Overall: Positive

Strengths

  • Improved adenoma detection rates (ADR) reported in clinical studies.
  • Real-time polyp detection and characterization assistance.
  • Potential to reduce missed polyps and improve diagnostic accuracy.
  • Augments endoscopist capabilities, especially for less experienced practitioners.
  • Non-invasive integration with existing endoscopy systems.
  • Aids in standardizing detection across different operators.

Limitations

  • Potential for 'alert fatigue' if too many false positives occur.
  • Reliance on AI technology, which may have limitations in certain edge cases.
  • Cost of implementation and integration into healthcare systems.
  • Requires training for medical staff to effectively utilize the system.
  • Limited long-term real-world data from widespread clinical use.
  • Ethical considerations regarding AI's role in medical decision-making.

Based on reviews from: MAGENTIQ website, Clinical trial publications (e.g., Gastroenterology, Endoscopy), Medical technology news outlets, Healthcare IT reviews (general industry discussions), Physician forums (discussions on AI in endoscopy)

Last updated: 2026-07-18

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Press & Coverage

MAGENTIQ EYE
MAGENTIQ EYE Releases New MAGENTIQ-COLOu2122 Versions Expanding User Experience and AI-Based Quality Metrics in Colonoscopy
MAGENTIQ EYE has released two upgraded versions of MAGENTIQ-COLOu2122, strengthening its AI-powered colonoscopy platform across both the U.S. and European markets with improved user experience and AI-based quality metrics.
2026-01
FirstWord HealthTech
MAGENTIQ EYE raises series A to scale AI colonoscopy platform
MAGENTIQ EYE has successfully completed its Series A funding round, led by aMoon, to accelerate the development and global rollout of its AI-powered colonoscopy platform, MAGENTIQ-COLOu2122, focusing on US and EU markets.
2025-08
PR Newswire
Lancet Digital Health Publishes Study Confirming MAGENTIQ-COLOu2122 AI-aided Colonoscopy Technology Improves Adenoma Detection Rates
A comprehensive study on MAGENTIQ-COLOu2122's performance, published in The Lancet Digital Health, validates its high level of performance in AI-aided colonoscopy by increasing adenoma detection rates and decreasing adenoma miss rates.
2024-02
Medical Device Network
Magentiq's AI-aided colonoscopy tool increases adenoma detection by 7%
Data from a multicenter clinical trial published in The Lancet Digital Health demonstrated that Magentiq-Colo, an AI-aided colonoscopy tool, significantly improved adenoma detection rates by 7% (absolute value) and reduced the adenoma miss rate by 17% (absolute value).
2024-02
BioSpace
FDA Authorizes Marketing of MAGENTIQ-COLOu2122, a Cutting-Edge AI Gastrointestinal Lesion Software Detection System that Helps Detect Lesions in Real Time During Colonoscopy Procedures
The U.S. Food and Drug Administration (FDA) has cleared MAGENTIQ-COLOu2122 via the 510(k) process, making it one of the few AI solutions approved for colonoscopy and the first to provide clinicians with an indication of lesion size, type, and maturity.
2023-07
UTHSC News
Chattanooga Research Team Plays Pivotal Role in International Study of AI-Guided Colonoscopy System
A Chattanooga research team played a pivotal role in an international study that validated the effectiveness of MAGENTIQ-COLOu2122, showing a 7% increase in adenoma detection rate and a 19% decrease in adenoma miss rate.
2024-03
PMC (PubMed Central)
The role of artificial intelligence in gastroenterology: current perspectives and future directionsu2014narrative review
This narrative review discusses the significant impact of AI in gastroenterology, highlighting MAGENTIQ-COLOu2122 as a computer-aided detection (CADe) system with advanced features, FDA 510(k) clearance, CE Mark, and Israel AMAR approval.
2026-01
MAGENTIQ EYE
A new benchmark for AI aided colonoscopy
MAGENTIQ-COLOu2122 sets new standards for AI-aided colonoscopy, maintaining clinical workflow while providing gastroenterologists with real-time information on polyp detection, size, and type, and generating comprehensive post-procedure reports.
unknown

Videos

Product demos, reviews, and walkthroughs for MAGENTIQ-COLO™.

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Frequently Asked Questions

MAGENTIQ-COLOu2122 seamlessly integrates into the clinical workflow by acquiring digital video signals from the endoscopy tower and running deep learning algorithms in real-time. Its primary function is to aid gastroenterologists in detecting polyps by highlighting suspicious areas with a bounding box on the main or a separate screen, and providing additional information like size category and type.
MAGENTIQ-COLOu2122 has received CE Mark approval since 2021 and FDA clearance since 2023, indicating it meets established safety and performance standards for medical devices. These clearances allow its use in clinical practice within Europe and the United States, affirming its validated performance in improving adenoma detection rates.
While MAGENTIQ-COLOu2122 significantly increases adenoma detection, some missed adenomas in studies were not visible in the visual field, indicating inherent limitations in detecting obscured lesions. Studies also noted no significant increase in procedure or withdrawal time, though there was not a statistically significant increase in sessile serrated lesion detection compared to controls.
MAGENTIQ-COLOu2122 is recognized as one of several AI-aided colonoscopy solutions, alongside systems like Fujifilm's CAD EYE, Olympus' ENDO-AID, Wision AI's EndoScreener, and Medtronic's GI Genius. It has demonstrated a 7% absolute increase in adenoma detection rate and a 17% absolute decrease in adenoma miss rate, positioning it as a high-performing solution in the category.
The pricing model for MAGENTIQ-COLOu2122 is described as having a low upfront cost, flexible commitment, and includes automatic software updates. Economic benefits for practices can include additional income from more detected and resected adenomas, and potential savings on colorectal cancer treatment due to improved early detection.
MAGENTIQ-COLOu2122 is intended as an adjunct to the colonoscopy procedure and is not meant for diagnosis or characterization of lesions, nor does it replace clinical decision-making. The physician remains in complete control and makes all diagnostic and treatment decisions, with the AI serving as an assistive tool to enhance attentiveness and detection.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18

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